The directors and members of the Intelligent Clinical Care Center (IC3) have published over 1,500 articles in peer-reviewed, scholarly journals. These include journals such as Nature Reviews Nephrology, Scientific Reports, JAMA Internal Medicine, JAMA Network Open, The Lancet Digital Health, Medical Image Analysis, BMJ Health & Care Informatics, PLOS ONE, Kidney International, and Surgery.
Listed below are recent publications from some of the IC3 member labs. For more information on publications by specific IC3 members or labs, please refer to the IC3 Members page or the IC3 Labs page.
PRISMAP
IC3 director Azra Bihorac, associate directors of research Tyler Loftus and Tezcan Ozrazgat Baslanti, and assistant director of clinical AI Benjamin Shickel are all part of the Precision and Intelligent Systems in Medicine Research Partnership (PRISMAP) in the UF College of Medicine.
CONCLUSION: While AI holds promise for enhancing ACS, current applications are narrowly focused on pre-operative risk prediction using limited data modalities. Future efforts must prioritize prospective validation, real-time dynamic predictions,…
CONCLUSIONS: AI has the potential to complement emergency surgeons’ clinical judgment, but its routine adoption in emergency surgical practice remains limited. Addressing methodological, ethical, and regulatory challenges, together with the…
Sepsis remains a leading cause of morbidity and mortality worldwide, with survivors often following divergent trajectories: rapid recovery (RAP) or progression to chronic critical illness (CCI). CCI is characterized by…
i-Heal Lab
IC3 co-director Parisa Rashidi leads the Intelligent Health Systems (i-Heal) Lab in the UF Herbert Wertheim College of Engineering.
CONCLUSIONS: In a large cohort of patients with claudication, patients with ADRD demonstrate higher risk of all-cause mortality. Among patients who undergo revascularization for claudication, patients with ADRD have worse…
Colorectal cancer (CRC) is a genetically varied malignancy noted for its metabolic flexibility, which enables cancer cells to adapt to different energy sources. Beta-hydroxybutyrate (BHB), a significant ketone body that…
CONCLUSION: Variable selection is a key component of prognostic model development study. Based on expert recommendations that highlight the use of clinical expertise in variable selection, we conducted a rigorous…
CONCLUSION: The AICC workshop successfully advanced AI literacy among biomedical professionals and promoted collaborative peer networks. Continued efforts are recommended to enhance participant engagement and ensure equitable access to AI…
CMI Lab
IC3 associate director of research Pinaki Sarder leads the Computational Microscopy Imaging (CMI) Lab in the UF College of Medicine.
Assessment of interstitial fibrosis is essential in the diagnosis and prognosis of kidney diseases. However, current histologic scoring methods using trichrome-stained slides are limited by inter-observer variability and inconsistent stain…
Frozen section biopsies stained with Hematoxylin & Eosin (H&E) are standard for assessing donor kidneys but are often interpreted by general pathologists with limited renal expertise, and hindered by freezing…
SMILE Lab
IC3 associate director of education Ruogu Fang leads the Smart Medical Informatics Learning and Evaluation (SMILE) Lab in the UF Herbert Wertheim College of Engineering.
Perfusion imaging is extensively utilized to assess hemodynamic status and tissue perfusion in various organs. Computed tomography perfusion (CTP) imaging plays a key role in the early assessment and planning…
Perfusion imaging is extensively utilized to assess hemodynamic status and tissue perfusion in various organs. Computed tomography perfusion (CTP) imaging plays a key role in the early assessment and planning…
Dynamic brain data are becoming increasingly accessible, providing a gateway to understanding the inner workings of the brain in living participants. However, the size and complexity of the data pose…
Deep brain stimulation (DBS) is a highly effective treatment for movement disorders like Parkinson’s disease, essential tremor, and dystonia. However, the current multidisciplinary workflow for implanting and programming DBS is…