The directors and members of the Intelligent Clinical Care Center (IC3) have published over 1,500 articles in peer-reviewed, scholarly journals. These include journals such as Nature Reviews Nephrology, Scientific Reports, JAMA Internal Medicine, JAMA Network Open, The Lancet Digital Health, Medical Image Analysis, BMJ Health & Care Informatics, PLOS ONE, Kidney International, and Surgery.
Listed below are recent publications from some of the IC3 member labs. For more information on publications by specific IC3 members or labs, please refer to the IC3 Members page or the IC3 Labs page.
PRISMAP
IC3 director Azra Bihorac, associate directors of research Tyler Loftus and Tezcan Ozrazgat Baslanti, and assistant director of clinical AI Benjamin Shickel are all part of the Precision and Intelligent Systems in Medicine Research Partnership (PRISMAP) in the UF College of Medicine.
CONCLUSION: PM is a biologically plausible, modifiable contributor to SSI development. Current approaches optimize room-level air metrics that correlate poorly with biologically relevant pathogen exposure at the surgical field. Dynamic,…
CONCLUSION: Graduate medical education trainees demonstrated high artificial intelligence exposure but low confidence, with formal training being rare. The familiarity-confidence gap suggests that passive exposure does not confer confidence. Uniform…
Recent years have seen a surge in the development of Artificial Intelligence (AI) technologies to enhance intraoperative decision-making and improve patient safety. Yet, real-world evidence on their implementation remains limited.…
i-Heal Lab
IC3 co-director Parisa Rashidi leads the Intelligent Health Systems (i-Heal) Lab in the UF Herbert Wertheim College of Engineering.
IntroductionRestoring normal gait function remains a major clinical challenge in post-stroke rehabilitation. Backward walking may increase neuromotor demands compared with forward walking and performing it on an incline may further…
CONCLUSIONS: Our findings suggest that implementation of the model’s policy has the potential to lower postoperative AKI and improve other outcomes driven by intraoperative hypotension.
CONCLUSIONS AND RELEVANCE: A model using routinely collected variables from a large multicenter cohort was developed and validated, demonstrating accurate prediction of postoperative complications and death with generalizability across a…
CONCLUSIONS: In a large cohort of patients with claudication, patients with ADRD demonstrate a higher risk of all-cause mortality. Among patients who undergo revascularization for claudication, patients with ADRD have…
CMI Lab
IC3 associate director of research Pinaki Sarder leads the Computational Microscopy Imaging (CMI) Lab in the UF College of Medicine.
Identifying cell types present in lung biopsies can provide critical information on pathological processes, tissue organization, and organ health, and are valuable in both clinical and research settings. Knowledge of…
Light microscopy imaging with histological stains is central to disease diagnosis and research. It is enhanced with immunostaining to reveal cellular composition and complexity linked to clinical utility and biological…
CONCLUSIONS: We demonstrate the feasibility of using AI-based FTU segmentation integrated with spatial transcriptomics-derived immune cell proportions to generate spatially informed t- and g-scores aligned with Banff criteria, with full…
Artificial intelligence now plays a central role in computational pathology, enabling large-scale analysis of whole slide images for segmentation, classification, and quantitative feature extraction. Despite these advances, the development of…
SMILE Lab
IC3 associate director of education Ruogu Fang leads the Smart Medical Informatics Learning and Evaluation (SMILE) Lab in the UF Herbert Wertheim College of Engineering.
This Perspective outlines the challenges addressed at the first Annual Parkinson’s Disease (PD) Prevention Think Tank, held on November 20-21, 2025 in Gainesville, Florida at the Fixel Institute. Over the…
BackgroundThe systemic, metabolic, lifestyle factors have established associations with Alzheimer’s disease (AD) through epidemiologic and AD-specific biomarker studies. Whether colored fundus photography (CFP) contains retinal structural signatures corresponding to these…
Foundation models (FMs) in AI have garnered significant attention and demonstrated substantial potential across a broad range of applications. However, applying them to specific domains like biomedical imaging often necessitates…