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About Rui Yin
My research mainly focuses on applying and developing machine learning approaches (CNN, RNN, GNN, Transformer, etc.) and protein language models to address biomedical problems, especially in (1) RNA virus and infectious diseases, e.g., PPI prediction, mutation and variant identification, viral antigenicity and virulence prediction; (2) rare disease study, e.g., variant pathogenicity prediction and gene prioritization; (3) cancer study, e.g., miRNA-mRNA target identification in colorectal cancer patients and renal tumor classification, (4) Alzheimer’s disease and related dementias (AD/ADRD), e.g., computational drug repurposing for AD/ADRD; and (5) Health equity, e.g., identify social determinants of health that impact healthy aging people.
Teaching Profile
Courses Taught
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GMS6805 – Information Modeling in Biomedicine
College of Medicine
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GMS6850 – Foundations of Biomedical Informatics
College of Medicine
Research Profile
0000-0002-1403-0396
Areas of Interest
- Biomedical informatics
- Genomics and precision medicine
- Health Equity
- Machine learning and applications
- Protein language model
Publications
Academic Articles
Grants
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Decipher microRNA mis-regulation in Colorectal Cancer via Semantic Embedded Graph Neural Networks
Active
- Role:
- Principal Investigator
- Funding:
- FL DEPT OF HLTH BANKHEAD-COLEY CANCER RE
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Integrating genetics and health data to discover common drug effects on cancer and Alzheimer’s disease
- Role:
- Principal Investigator
- Funding:
- UNIVERSITY OF MASSACHUSETTS LOWELL via NATL INST OF HLTH NIGMS
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Deciphering Dysregulated RNA Interference in Colorectal Cancer via Semantic Embedded Graph Neural Networks
- Role:
- Principal Investigator
- Funding:
- PARDEE FOU, ELSA U
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UF HEALTH CANCER CENTER PILOT PROJECTS GRANTS FUNDED THROUGHTHE FLORIDA CONSORTIUM OF NATIONAL CANCER INSTITUTE CENTER
Active
- Role:
- Project Manager
- Funding:
- UF HEALTH SHANDS HOSPITAL
Education
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Postdoc
Harvard Medical School
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Ph.D.
Nanyang Technological University
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Master
Central South University
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Bachelor
Shandong University
Contact Details
- Business:
- ruiyin@ufl.edu
- Business Mailing:
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PO Box 100147
Gainesville FL 32610 - Business Street:
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1889 MUSEUM RD STE 7102
GAINESVILLE FL 32611